TY - JOUR
T1 - The dawn phenomenon, an early morning glucose rise
T2 - Implications for diabetic intraday blood glucose variation
AU - Schmidt, M. I.
AU - Hadji-Georgopoulos, A.
AU - Rendell, M.
AU - Margolis, S.
AU - Kowarski, A.
PY - 1981
Y1 - 1981
N2 - Eleven insulin-dependent (type I) diabetic subjects were studied during a 24-h period to assess intraday blood glucose (BG) variation and related free insulin (FI) levels. Ten patients exhibited the dawn phenomenon, a rise in early morning fasting blood glucose (123 ± 81.1 m/dl; mean ± SD). This increase was positively and significantly correlated with the morning postprandial BG peak (r=0.723; P=0.012). FI/BG ratios were highest during the night (0.717 and 0.666 at 2200 and 0400 h, respectively) and lowest during the early morning (0.294 at 0800 h) (P
AB - Eleven insulin-dependent (type I) diabetic subjects were studied during a 24-h period to assess intraday blood glucose (BG) variation and related free insulin (FI) levels. Ten patients exhibited the dawn phenomenon, a rise in early morning fasting blood glucose (123 ± 81.1 m/dl; mean ± SD). This increase was positively and significantly correlated with the morning postprandial BG peak (r=0.723; P=0.012). FI/BG ratios were highest during the night (0.717 and 0.666 at 2200 and 0400 h, respectively) and lowest during the early morning (0.294 at 0800 h) (P
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U2 - 10.2337/diacare.4.6.579
DO - 10.2337/diacare.4.6.579
M3 - Article
C2 - 6751733
AN - SCOPUS:0019857081
SN - 0375-9474
VL - 4
SP - 579
EP - 585
JO - Nuclear Physics A
JF - Nuclear Physics A
IS - 6
ER -