Prospective trial of oestrogen and calcium in postmenopausal women

A. Horsman, J. C. Gallagher, M. Simpson, B. E.C. Nordin

Research output: Contribution to journalArticlepeer-review

272 Scopus citations

Abstract

In a prospective trial in 72 postmenopausal women to compare the effects on bone loss of no treatment, treatment with oestrogen, and treatment with cal cium the women were followed up for at least two years and examined densitometrically and morphometrically. Women in the untreated control group continued to lose bone during the two years, whereas the oestrogen-treated group lost none. Loss in the calcium-treated group was intermediate. Oestrogen appeared to inhibit endosteal bone resorption and may have stimulated subperiosteal bone apposition.

Original languageEnglish (US)
Pages (from-to)789-792
Number of pages4
JournalBritish Medical Journal
Volume2
Issue number6090
DOIs
StatePublished - Sep 1977
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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