Potential influence of timing of low-density lipoprotein cholesterol evaluation in patients with acute coronary syndrome

Michele A. Faulkner; Daniel E. Hilleman; Christopher J. Destache; Aryan N. Mooss

doi:10.1592/phco.21.13.1055.34614

Potential influence of timing of low-density lipoprotein cholesterol evaluation in patients with acute coronary syndrome

Michele A. Faulkner, Daniel E. Hilleman, Christopher J. Destache, Aryan N. Mooss

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Objective. To determine the significance of timing of low-density lipoprotein (LDL) cholesterol evaluation in patients with chest pain as it relates to subsequent National Cholesterol Education Program (NCEP) treatment decisions. Design. Prospective, observational study. Setting. A university-affiliated tertiary care hospital. Patients. Sixty-two patients with coronary heart disease who were not receiving lipid-lowering therapy and whose LDL levels were obtained 25-48 hours after onset of chest pain. Intervention. We evaluated laboratory test results of patients with chest pain admitted to the cardiac care unit to determine risk to patients when LDL levels obtained inappropriately are used to make decisions regarding antihyperlipidemic therapy. Measurements and Main Results. Inpatient and outpatient LDL levels were compared, and changes in NCEP treatment decisions analyzed. Differences between inpatient and outpatient LDL levels were significant (p

Original language	English (US)
Pages (from-to)	1055-1060
Number of pages	6
Journal	Pharmacotherapy
Volume	21
Issue number	9I
DOIs	https://doi.org/10.1592/phco.21.13.1055.34614
State	Published - Jan 1 2001

All Science Journal Classification (ASJC) codes

Pharmacology (medical)

Access to Document

10.1592/phco.21.13.1055.34614

Cite this

@article{1efbd86364e5425bb9ba572789b076d0,

title = "Potential influence of timing of low-density lipoprotein cholesterol evaluation in patients with acute coronary syndrome",

abstract = "Objective. To determine the significance of timing of low-density lipoprotein (LDL) cholesterol evaluation in patients with chest pain as it relates to subsequent National Cholesterol Education Program (NCEP) treatment decisions. Design. Prospective, observational study. Setting. A university-affiliated tertiary care hospital. Patients. Sixty-two patients with coronary heart disease who were not receiving lipid-lowering therapy and whose LDL levels were obtained 25-48 hours after onset of chest pain. Intervention. We evaluated laboratory test results of patients with chest pain admitted to the cardiac care unit to determine risk to patients when LDL levels obtained inappropriately are used to make decisions regarding antihyperlipidemic therapy. Measurements and Main Results. Inpatient and outpatient LDL levels were compared, and changes in NCEP treatment decisions analyzed. Differences between inpatient and outpatient LDL levels were significant (p",

author = "Faulkner, {Michele A.} and Hilleman, {Daniel E.} and Destache, {Christopher J.} and Mooss, {Aryan N.}",

year = "2001",

month = jan,

day = "1",

doi = "10.1592/phco.21.13.1055.34614",

language = "English (US)",

volume = "21",

pages = "1055--1060",

journal = "Pharmacotherapy",

issn = "0277-0008",

publisher = "Pharmacotherapy Publications Inc.",

number = "9I",

}

TY - JOUR

T1 - Potential influence of timing of low-density lipoprotein cholesterol evaluation in patients with acute coronary syndrome

AU - Faulkner, Michele A.

AU - Hilleman, Daniel E.

AU - Destache, Christopher J.

AU - Mooss, Aryan N.

PY - 2001/1/1

Y1 - 2001/1/1

N2 - Objective. To determine the significance of timing of low-density lipoprotein (LDL) cholesterol evaluation in patients with chest pain as it relates to subsequent National Cholesterol Education Program (NCEP) treatment decisions. Design. Prospective, observational study. Setting. A university-affiliated tertiary care hospital. Patients. Sixty-two patients with coronary heart disease who were not receiving lipid-lowering therapy and whose LDL levels were obtained 25-48 hours after onset of chest pain. Intervention. We evaluated laboratory test results of patients with chest pain admitted to the cardiac care unit to determine risk to patients when LDL levels obtained inappropriately are used to make decisions regarding antihyperlipidemic therapy. Measurements and Main Results. Inpatient and outpatient LDL levels were compared, and changes in NCEP treatment decisions analyzed. Differences between inpatient and outpatient LDL levels were significant (p

AB - Objective. To determine the significance of timing of low-density lipoprotein (LDL) cholesterol evaluation in patients with chest pain as it relates to subsequent National Cholesterol Education Program (NCEP) treatment decisions. Design. Prospective, observational study. Setting. A university-affiliated tertiary care hospital. Patients. Sixty-two patients with coronary heart disease who were not receiving lipid-lowering therapy and whose LDL levels were obtained 25-48 hours after onset of chest pain. Intervention. We evaluated laboratory test results of patients with chest pain admitted to the cardiac care unit to determine risk to patients when LDL levels obtained inappropriately are used to make decisions regarding antihyperlipidemic therapy. Measurements and Main Results. Inpatient and outpatient LDL levels were compared, and changes in NCEP treatment decisions analyzed. Differences between inpatient and outpatient LDL levels were significant (p

UR - http://www.scopus.com/inward/record.url?scp=0034876653&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034876653&partnerID=8YFLogxK

U2 - 10.1592/phco.21.13.1055.34614

DO - 10.1592/phco.21.13.1055.34614

M3 - Article

C2 - 11560195

AN - SCOPUS:0034876653

SN - 0277-0008

VL - 21

SP - 1055

EP - 1060

JO - Pharmacotherapy

JF - Pharmacotherapy

IS - 9I

ER -

Potential influence of timing of low-density lipoprotein cholesterol evaluation in patients with acute coronary syndrome

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this