MULTICENTRIC RETICULOHISTIOCYTOSIS IN A PATIENT WITH MALIGNANT MELANOMA: A RESPONSE TO CYCLOPHOSPHAMIDE AND A UNIQUE CUTANEOUS FEATURE

Jay G. Kenik, Christopher J. Huerter, John A. Hurley, James F. Stanosheck

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Abstract

We describe a patient with multicentric reticulohistiocytosis and a history of malignant melanoma. His widely disseminated disease did not affect the site of surgical removal of the malignant melanoma nor the donor site of a skin graft. The multicentric reticulohistiocytosis progressed while the patient was taking nonsteroidal antiinflammatory agents, but showed significant response during a 10-month course of cyclophosphamide. While he was taking the cyclophosphamide, however, his melanoma recurred, and the patient subsequently died.

Original languageEnglish (US)
Pages (from-to)1047-1051
Number of pages5
JournalArthritis & Rheumatism
Volume33
Issue number7
DOIs
StatePublished - Jul 1990

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

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