Low serum IgA in a familial ovarian cancer aggregate

Guy S. Schuelke; Henry T. Lynch; Jane F. Lynch; Pamela R. Fain; Edward A. Chaperon

doi:10.1016/0165-4608(82)90060-7

Low serum IgA in a familial ovarian cancer aggregate

Guy S. Schuelke, Henry T. Lynch, Jane F. Lynch, Pamela R. Fain, Edward A. Chaperon

Department of Preventive Medicine

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Low serum IgA levels were found to segregate in a sufficient number of individuals from a familial ovarian carcinoma aggregate to suggest that this may be a genetically determined immune defect etiologically integral to cancer susceptibility in this family. The putative role of IgA in pathogenesis remains elusive. Cancer-prone families should be thoroughly investigated for further elucidation of these phenomena.

Original language	English (US)
Pages (from-to)	231-236
Number of pages	6
Journal	Cancer Genetics and Cytogenetics
Volume	6
Issue number	3
DOIs	https://doi.org/10.1016/0165-4608(82)90060-7
State	Published - Jul 1982

All Science Journal Classification (ASJC) codes

Molecular Biology
Genetics
Cancer Research

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10.1016/0165-4608(82)90060-7

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title = "Low serum IgA in a familial ovarian cancer aggregate",

abstract = "Low serum IgA levels were found to segregate in a sufficient number of individuals from a familial ovarian carcinoma aggregate to suggest that this may be a genetically determined immune defect etiologically integral to cancer susceptibility in this family. The putative role of IgA in pathogenesis remains elusive. Cancer-prone families should be thoroughly investigated for further elucidation of these phenomena.",

author = "Schuelke, {Guy S.} and Lynch, {Henry T.} and Lynch, {Jane F.} and Fain, {Pamela R.} and Chaperon, {Edward A.}",

note = "Funding Information: This work was supported by the Elsa U. Pardee Foundation and the Council for Tobacco Research, USA, Inc., Grant 1297M.",

year = "1982",

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doi = "10.1016/0165-4608(82)90060-7",

language = "English (US)",

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journal = "Cancer Genetics and Cytogenetics",

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T1 - Low serum IgA in a familial ovarian cancer aggregate

AU - Schuelke, Guy S.

AU - Lynch, Henry T.

AU - Lynch, Jane F.

AU - Fain, Pamela R.

AU - Chaperon, Edward A.

N1 - Funding Information: This work was supported by the Elsa U. Pardee Foundation and the Council for Tobacco Research, USA, Inc., Grant 1297M.

PY - 1982/7

Y1 - 1982/7

N2 - Low serum IgA levels were found to segregate in a sufficient number of individuals from a familial ovarian carcinoma aggregate to suggest that this may be a genetically determined immune defect etiologically integral to cancer susceptibility in this family. The putative role of IgA in pathogenesis remains elusive. Cancer-prone families should be thoroughly investigated for further elucidation of these phenomena.

AB - Low serum IgA levels were found to segregate in a sufficient number of individuals from a familial ovarian carcinoma aggregate to suggest that this may be a genetically determined immune defect etiologically integral to cancer susceptibility in this family. The putative role of IgA in pathogenesis remains elusive. Cancer-prone families should be thoroughly investigated for further elucidation of these phenomena.

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U2 - 10.1016/0165-4608(82)90060-7

DO - 10.1016/0165-4608(82)90060-7

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AN - SCOPUS:0020352296

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EP - 236

JO - Cancer Genetics and Cytogenetics

JF - Cancer Genetics and Cytogenetics

IS - 3

ER -

Low serum IgA in a familial ovarian cancer aggregate

Abstract

All Science Journal Classification (ASJC) codes

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