Low serum IgA in a familial ovarian cancer aggregate

Guy S. Schuelke, Henry T. Lynch, Jane F. Lynch, Pamela R. Fain, Edward A. Chaperon

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Low serum IgA levels were found to segregate in a sufficient number of individuals from a familial ovarian carcinoma aggregate to suggest that this may be a genetically determined immune defect etiologically integral to cancer susceptibility in this family. The putative role of IgA in pathogenesis remains elusive. Cancer-prone families should be thoroughly investigated for further elucidation of these phenomena.

Original languageEnglish (US)
Pages (from-to)231-236
Number of pages6
JournalCancer Genetics and Cytogenetics
Issue number3
StatePublished - Jul 1982

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics
  • Cancer Research


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