Identification of Cisplatin-Binding Proteins Using Agarose Conjugates of Platinum Compounds

Medicine & Life Sciences

• Platinum Compounds 100%
• Sepharose 71%
• Cisplatin 61%
• Carrier Proteins 57%
• Proteins 16%
• Chlorides 16%
• Platinum 15%
• Drug Interactions 14%
• ribosomal protein L5 14%
• Valosin Containing Protein 12%
• Nonmuscle Myosin Type IIA 12%
• Coomassie blue 11%
• Calreticulin 10%
• glucose-regulated proteins 10%
• HSP90 Heat-Shock Proteins 9%
• Ototoxicity 9%
• DNA 8%
• Cochlea 7%
• Protein Binding 7%
• Neoplasms 7%
• Antineoplastic Agents 7%
• Electrophoresis 7%
• Gels 6%
• Staining and Labeling 4%
• Kidney 4%
• Pharmaceutical Preparations 3%

Agriculture & Biology

• cisplatin 88%
• platinum 83%
• agarose 60%
• binding proteins 58%
• proteins 20%
• drugs 15%
• chlorides 12%
• neoplasms 11%
• calreticulin 10%
• drug interactions 10%
• heat-shock protein 90 10%
• nephrotoxicity 9%
• protein binding 8%
• ribosomal proteins 8%
• kidney cells 8%
• myosin 7%
• selectivity (chemistry) 7%
• DNA 7%
• neoplasm cells 6%
• gel electrophoresis 6%
• adverse effects 6%
• staining 5%
• toxicity 5%
• glucose 4%
• assays 4%
• cells 2%

Chemical Compounds

• Agarose 71%
• Cisplatin 59%
• Platinum 49%
• Protein 28%
• Ototoxic 12%
• Nephrotoxic 10%
• Resistance 8%
• Chloride 7%
• Gel Electrophoresis 6%
• Antineoplastic Agent 6%
• Amino Groups 5%
• Heat 5%
• Blue 4%