Generation of leukotriene B4 and C4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects

F. Kohi; H. Miyagawa; D. K. Agrawal; A. K. Bewtra; R. G. Townley

Generation of leukotriene B₄ and C₄ from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects

F. Kohi, H. Miyagawa, D. K. Agrawal, A. K. Bewtra, R. G. Townley

Department of Medicine

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

We determined the relationship of allergic disease to the number and activity of eosinophils and their production of leukotriene B₄ and leukotriene C₄ (leukotriene D₄ equivalents). Granulocytes from allergic rhinitis (AR) subjects and asthmatics release more LTC₄ than normals. Furthermore, eosinophils of astmatics generate more LTC₄ than those of AR subjects.

Original language	English (US)
Pages (from-to)	228-232
Number of pages	5
Journal	Annals of allergy
Volume	65
Issue number	3
State	Published - Jan 1 1990

All Science Journal Classification (ASJC) codes

Immunology and Allergy

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abstract = "We determined the relationship of allergic disease to the number and activity of eosinophils and their production of leukotriene B4 and leukotriene C4 (leukotriene D4 equivalents). Granulocytes from allergic rhinitis (AR) subjects and asthmatics release more LTC4 than normals. Furthermore, eosinophils of astmatics generate more LTC4 than those of AR subjects.",

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AU - Kohi, F.

AU - Miyagawa, H.

AU - Agrawal, D. K.

AU - Bewtra, A. K.

AU - Townley, R. G.

PY - 1990/1/1

Y1 - 1990/1/1

N2 - We determined the relationship of allergic disease to the number and activity of eosinophils and their production of leukotriene B4 and leukotriene C4 (leukotriene D4 equivalents). Granulocytes from allergic rhinitis (AR) subjects and asthmatics release more LTC4 than normals. Furthermore, eosinophils of astmatics generate more LTC4 than those of AR subjects.

AB - We determined the relationship of allergic disease to the number and activity of eosinophils and their production of leukotriene B4 and leukotriene C4 (leukotriene D4 equivalents). Granulocytes from allergic rhinitis (AR) subjects and asthmatics release more LTC4 than normals. Furthermore, eosinophils of astmatics generate more LTC4 than those of AR subjects.

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ER -

Generation of leukotriene B₄ and C₄ from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects

Abstract

All Science Journal Classification (ASJC) codes

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