Amniotic fluid embolism: Historical perspectives & new possibilities

Anne M. Schoening

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Amniotic fluid embolism (AFE) is a rare obstetric catastrophe that occurs suddenly and without warning. AFE is a condition that is poorly understood and often difficult to diagnose, but has a high maternal and neonatal morbidity and mortality. Since it was first described in 1926, the underlying pathophysiology has eluded researchers and clinicians. While a new understanding of the syndrome has emerged with the advent of a national registry in the 1980s, recommendations for diagnostic methods and treatment in the acute phase of the event remain unclear.The purpose of this article is to provide the reader with a historical look at the phenomenon of AFE, a description of its suspected pathophysiology, and recommendations for nursing interventions. A review of data from the national registry and other classic studies are included.

Original languageEnglish (US)
Pages (from-to)78-85
Number of pages8
JournalMCN The American Journal of Maternal/Child Nursing
Issue number2
StatePublished - Aug 2 2006

All Science Journal Classification (ASJC) codes

  • Pharmacology (nursing)
  • Maternity and Midwifery


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