25-hydroxyvitamin D in the range of 20 to 100 ng/mL and incidence of kidney stones

Stacie Nguyen, Leo Baggerly, Christine French, Robert P. Heaney, Edward D. Gorham, Cedric F. Garland

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Objectives. Increasing 25-hydroxyvitamin D serum levels can prevent a wide range of diseases. There is a concern about increasing kidney stone risk with vitamin D supplementation. We used Grassroots Health data to examine the relationship between vitamin D status and kidney stone incidence. Methods. The study included 2012 participants followed prospectively for a median of 19 months. Thirteen individuals self-reported kidney stones during the study period. Multivariate logistic regression was applied to assess the association between vitamin D status and kidney stones. Results. We found no statistically significant association between serum 25-hydroxyvitamin D and kidney stones (P = .42). Body mass index was significantly associated with kidney stone risk (odds ratio = 3.5; 95% confidence interval = 1.1, 11.3). Conclusions. We concluded that a serum 25-hydroxyvitamin D level of 20 to 100 nanograms per milliliter has no significant association with kidney stone incidence.

Original languageEnglish (US)
Pages (from-to)1783-1787
Number of pages5
JournalAmerican Journal of Public Health
Volume104
Issue number9
DOIs
StatePublished - Sep 2014

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

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