Department of Clinical Research and Public Health

Research output

Research output per year 1987 2007 2014 2015 2016 2017 2018 2022

• 169 Article
• 84 Review article
• 3 Editorial
• 3 Letter
• 4 More
  • 2 Comment/debate
  • 1 Chapter
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2004

  Increased expression and activation of CD30 induce apoptosis in human blood eosinophils

  Berro, A. I., Perry, G. A. & Agrawal, D. K., Aug 1 2004, In: Journal of Immunology. 173, 3, p. 2174-2183 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophils 100%
  • Apoptosis 62%
  • Asthma 18%
  • Interleukin-5 17%
  • Propidium 9%
  12 Scopus citations

• Influence of apoptosis on neurological outcome following traumatic cerebral contusion

  Nathoo, N., Narotam, P. K., Agrawal, D. K., Connolly, C. A., Van Dellen, J. R., Barnett, G. H. & Chetty, R., Aug 2004, In: Journal of Neurosurgery. 101, 2, p. 233-240 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Brain Contusion 100%
  • Apoptosis 42%
  • Caspase 3 35%
  • Traumatic Brain Injury 29%
  • Glasgow Outcome Scale 26%
  54 Scopus citations

• Novel immunomodulatory oligonucleotides prevent development of allergic airway inflammation and airway hyperresponsiveness in asthma

  Agrawal, D. K., Edwan, J., Kandimalla, E. R., Yu, D., Bhagat, L., Wang, D. & Agrawal, S., Jan 2004, In: International Immunopharmacology. 4, 1, p. 127-138 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Oligonucleotides 100%
  • Asthma 74%
  • Inflammation 56%
  • Ovalbumin 40%
  • Bronchoalveolar Lavage Fluid 25%
  36 Scopus citations

• "Vulnerable plaques" - Ticking of the time bomb

  Mitra, A. K., Dhume, A. S. & Agrawal, D. K., Oct 2004, In: Canadian Journal of Physiology and Pharmacology. 82, 10, p. 860-871 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Apoptosis 100%
  • Rupture 93%
  • Atherosclerotic Plaques 57%
  • Clinical Protocols 54%
  • Vascular Smooth Muscle 53%
  28 Scopus citations
• 2005

  Controlling cytokine signaling by constitutive inhibitors

  Rakesh, K. & Agrawal, D. K., Sep 1 2005, In: Biochemical Pharmacology. 70, 5, p. 649-657 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Protein Inhibitors of Activated STAT 100%
  • Cytokines 70%
  • Phosphoric Monoester Hydrolases 57%
  • Ubiquitin 57%
  • Protein 47%
  103 Scopus citations

• Engineering and characterization of a divalent single-chain Fv angiotensin II fusion construct of the monoclonal antibody CC49

  Wittel, U. A., Jain, M., Goel, A., Baranowska-Kortylewicz, J., Kurizaki, T., Chauhan, S. C., Agrawal, D. K., Colcher, D. & Batra, S. K., Apr 1 2005, In: Biochemical and Biophysical Research Communications. 329, 1, p. 168-176 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Single-Chain Antibodies 100%
  • Angiotensin II 98%
  • Monoclonal Antibodies 56%
  • KA-107 25%
  • Angiotensin 24%
  12 Scopus citations

• Evidence that insulin-like growth factor-1 requires protein kinase C-ε, PI3-kinase and mitogen-activated protein kinase pathways to protect human vascular smooth muscle cells from apoptosis

  Allen, T. R., Krueger, K. D., Hunter, W. J. & Agrawal, D. K., Dec 2005, In: Immunology and Cell Biology. 83, 6, p. 651-667 17 p.

  Research output: Contribution to journal › Article › peer-review

  • protein kinase C kinase 100%
  • Somatomedins 76%
  • Mitogen-Activated Protein Kinases 71%
  • Phosphatidylinositol 3-Kinases 71%
  • Vascular Smooth Muscle 71%
  43 Scopus citations

• Sustained Akt/PKB activation and transient attenuation of c-jun N-Terminal kinase in the inhibition of apoptosis by IGF-1 in vascular smooth muscle cells

  Allen, R. T., Krueger, K. D., Dhume, A. & Agrawal, D. K., May 2005, In: Apoptosis : an international journal on programmed cell death. 10, 3, p. 525-535 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Inhibition of Apoptosis 100%
  • JNK Mitogen-Activated Protein Kinases 60%
  • Somatomedins 57%
  • Vascular Smooth Muscle 52%
  • Smooth Muscle Myocytes 47%
  20 Scopus citations

• Treatment with Flt3 ligand plasmid reverses allergic airway inflammation in ovalbumin-sensitized and -challenged mice

  Edwan, J. H., Talmadge, J. E. & Agrawal, D. K., Feb 2005, In: International Immunopharmacology. 5, 2, p. 345-357 13 p.

  Research output: Contribution to journal › Article › peer-review

  • flt3 ligand protein 100%
  • Ovalbumin 74%
  • Plasmids 54%
  • Inflammation 39%
  • Methacholine Chloride 19%
  17 Scopus citations
• 2006

  Differential effects of insulin-like growth factor-1 and atheroma-associated cytokines on cell proliferation and apoptosis in plaque smooth muscle cells of symptomatic and asymptomatic patients with carotid stenosis

  Jia, G., Cheng, G. & Agrawal, D. K., Oct 2006, In: Immunology and Cell Biology. 84, 5, p. 422-429 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Carotid Stenosis 100%
  • Somatomedins 94%
  • Atherosclerotic Plaques 92%
  • Vascular Smooth Muscle 87%
  • Smooth Muscle Myocytes 77%
  30 Scopus citations

• Insulin-like growth factor-1 and TNF-α regulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells

  Jia, G., Cheng, G., Gangahar, D. M. & Agrawal, D. K., Oct 2006, In: Immunology and Cell Biology. 84, 5, p. 448-454 7 p.

  Research output: Contribution to journal › Article › peer-review

  • JNK Mitogen-Activated Protein Kinases 100%
  • Somatomedins 94%
  • Vascular Smooth Muscle 87%
  • Autophagy 85%
  • Smooth Muscle Myocytes 78%
  271 Scopus citations
• 2007

  Angiotensin II and IGF-1 Regulate Connexin43 Expression Via ERK and p38 Signaling Pathways in Vascular Smooth Muscle Cells of Coronary Artery Bypass Conduits

  Jia, G., Mitra, A. K., Cheng, G., Gangahar, D. M. & Agrawal, D. K., Sep 2007, In: Journal of Surgical Research. 142, 1, p. 137-142 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Connexin 43 100%
  • Insulin-Like Growth Factor I 82%
  • Vascular Smooth Muscle 80%
  • Angiotensin II 79%
  • Coronary Artery Bypass 78%
  27 Scopus citations

• Dendritic cells in allergic airway inflammation

  Bharadwaj, A. S., Bewtra, A. K. & Agrawal, D. K., Jul 2007, In: Canadian Journal of Physiology and Pharmacology. 85, 7, p. 686-699 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendritic Cells 100%
  • Inflammation 65%
  • Asthma 38%
  • fms-Like Tyrosine Kinase 3 20%
  • Guanine Nucleotides 15%
  28 Scopus citations

• Flt3 ligand generates morphologically distinct semimature dendritic cells in ovalbumin-sensitized mice

  Bharadwaj, A. S. & Agrawal, D. K., Aug 2007, In: Experimental and Molecular Pathology. 83, 1, p. 17-24 8 p.

  Research output: Contribution to journal › Article › peer-review

  • flt3 ligand protein 100%
  • Ovalbumin 74%
  • Methacholine 59%
  • Dendritic Cells 59%
  • Antigen 55%
  7 Scopus citations

• Flt3-ligand plasmid prevents the development of pathophysiological features of chronic asthma in a mouse model

  Edwan, J. H. & Agrawal, D. K., Feb 2007, In: Immunologic Research. 37, 2, p. 147-159 13 p.

  Research output: Contribution to journal › Article › peer-review

  • flt3 ligand protein 100%
  • Plasmids 54%
  • Asthma 52%
  • Inflammation 39%
  • Airway Remodeling 29%
  8 Scopus citations

• Increased expression of inhibitor of apoptosis proteins in atherosclerotic plaques of symptomatic patients with carotid stenosis

  Moran, E. P. & Agrawal, D. K., Aug 2007, In: Experimental and Molecular Pathology. 83, 1, p. 11-16 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Inhibitor of Apoptosis Proteins 100%
  • Carotid Stenosis 81%
  • Atherosclerotic Plaques 75%
  • Baculoviral IAP Repeat-Containing 3 Protein 40%
  • Protein 29%
  20 Scopus citations

• Insulin-like growth factor-I receptors in atherosclerotic plaques of symptomatic and asymptomatic patients with carotid stenosis: Effect of IL-12 and IFN-γ

  Jia, G., Cheng, G., Soundararajan, K. & Agrawal, D. K., Feb 2007, In: American Journal of Physiology - Heart and Circulatory Physiology. 292, 2

  Research output: Contribution to journal › Article › peer-review

  • IGF Type 1 Receptor 100%
  • Carotid Stenosis 89%
  • Atherosclerotic Plaques 82%
  • Interleukin-12 81%
  • Vascular Smooth Muscle 77%
  19 Scopus citations

• Involvement of chloride channels in IGF-I-induced proliferation of porcine arterial smooth muscle cells

  Cheng, G., Kim, M. J., Jia, G. & Agrawal, D. K., Jan 1 2007, In: Cardiovascular Research. 73, 1, p. 198-207 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Chloride Channels 100%
  • Insulin-Like Growth Factor I 80%
  • Smooth Muscle Myocytes 70%
  • Vascular Smooth Muscle 67%
  • Swine 62%
  32 Scopus citations

• Involvement of chloride channels in TGF-β1-induced apoptosis of human bronchial epithelial cells

  Cheng, G., Shao, Z., Chaudhari, B. & Agrawal, D. K., Nov 2007, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 293, 5

  Research output: Contribution to journal › Article › peer-review

  • Chloride Channels 100%
  • Transforming Growth Factors 83%
  • Epithelial Cells 56%
  • Apoptosis 48%
  • Chlorides 18%
  28 Scopus citations

• Recent advances in the immunobiology of ceramide

  Pandey, S., Murphy, R. F. & Agrawal, D. K., Jun 2007, In: Experimental and Molecular Pathology. 82, 3, p. 298-309 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Ceramide 100%
  • Ceramides 97%
  • Pharmacological Metabolism 18%
  • dihydroceramide desaturase 16%
  • Sphingomyelin 14%
  34 Scopus citations
• 2008

  Interaction of suplatast tosilate (IPD) with chloride channels in human blood eosinophils: A potential mechanism underlying its anti-allergic and anti-asthmatic effects

  Agrawal, D. K., Cheng, G., Kim, M. J. & Kiniwa, M., Feb 2008, In: Clinical and Experimental Allergy. 38, 2, p. 305-312 8 p.

  Research output: Contribution to journal › Article › peer-review

  • suplatast tosilate 100%
  • Anti-Asthmatic Agents 77%
  • Anti-Allergic Agents 70%
  • Chloride Channels 67%
  • Eosinophils 52%
  10 Scopus citations

• Intra and extravascular transmembrane signalling of angiopoietin-1-Tie2 receptor in health and disease: Molecular Medicine

  Makinde, T. & Agrawal, D. K., Jun 2008, In: Journal of Cellular and Molecular Medicine. 12, 3, p. 810-828 19 p.

  Research output: Contribution to journal › Article › peer-review

  • TIE-2 Receptor 100%
  • Molecular Medicine 88%
  • Angiopoietin-1 86%
  • Health 30%
  • Chemotactic 13%
  62 Scopus citations

• Involvement of connexin 43 in angiotensin II-induced migration and proliferation of saphenous vein smooth muscle cells via the MAPK-AP-1 signaling pathway

  Jia, G., Cheng, G., Gangahar, D. M. & Agrawal, D. K., May 2008, In: Journal of Molecular and Cellular Cardiology. 44, 5, p. 882-890 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Connexin 43 100%
  • Saphenous Vein 91%
  • Transcription Factor AP-1 90%
  • Mitogen-Activated Protein Kinases 81%
  • Angiotensin II 79%
  56 Scopus citations
• 2009

  Fms-like tyrosine kinase 3 ligand increases a lung DC subset with regulatory properties in allergic airway inflammation

  Shao, Z., Bharadwaj, A. S., McGee, H. S., Makinde, T. O. & Agrawal, D. K., Apr 2009, In: Journal of Allergy and Clinical Immunology. 123, 4

  Research output: Contribution to journal › Article › peer-review

  • flt3 ligand protein 100%
  • Dendritic Cells 59%
  • Ovalbumin 42%
  • Inflammation 39%
  • Lung 35%
  27 Scopus citations

• Fms-like tyrosine kinase 3 ligand regulates migratory pattern and antigen uptake of lung dendritic cell subsets in a murine model of allergic airway inflammation

  Shao, Z., Makinde, T. O., McGee, H. S., Wang, X. & Agrawal, D. K., Dec 1 2009, In: Journal of Immunology. 183, 11, p. 7531-7538 8 p.

  Research output: Contribution to journal › Article › peer-review

  • flt3 ligand protein 100%
  • Dendritic Cells 59%
  • Antigens 42%
  • Inflammation 39%
  • Lung 35%
  15 Scopus citations

• Naturally occurring and inducible T-regulatory cells modulating immune response in allergic asthma

  McGee, H. S. & Agrawal, D. K., Aug 1 2009, In: American Journal of Respiratory and Critical Care Medicine. 180, 3, p. 211-225 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Regulatory T-Lymphocytes 100%
  • Asthma 78%
  • Lung 53%
  • Interleukin-10 44%
  • Green Fluorescent Proteins 40%
  54 Scopus citations

• p53 amino-terminus region (1-125) stabilizes and restores heat denatured p53 wild phenotype

  Sharman, A. K., Ali, A., Gogna, R., Singh, A. K. & Pati, U., Oct 22 2009, In: PloS one. 4, 10, e7159.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hot Temperature 100%
  • Heat-Shock Response 95%
  • Transcriptional Activation 78%
  • Phenotype 77%
  • Noxae 63%
  8 Scopus citations

• Regulation of cell cycle entry by PTEN in smooth muscle cell proliferation of human coronary artery bypass conduits

  Jia, G., Mitra, A. K., Gangahar, D. M. & Agrawal, D. K., Mar 2009, In: Journal of Cellular and Molecular Medicine. 13, 3, p. 547-554 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Coronary Artery Bypass 100%
  • Smooth Muscle Myocytes 92%
  • Cell Cycle 82%
  • Saphenous Vein 78%
  • Cell Proliferation 69%
  19 Scopus citations

• Temporal PTEN inactivation causes proliferation of saphenous vein smooth muscle cells of human CABG conduits

  Mitra, A. K., Jia, G., Gangahar, D. M. & Agrawal, D. K., Jan 2009, In: Journal of Cellular and Molecular Medicine. 13, 1, p. 177-187 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Tensins 100%
  • Saphenous Vein 86%
  • Mammary Arteries 82%
  • Phosphoric Monoester Hydrolases 78%
  • Coronary Artery Bypass 73%
  19 Scopus citations
• 2010

  Expression of leukemia/lymphoma-related factor (LRF/POKEMON) in human breast carcinoma and other cancers

  Aggarwal, A., Hunter, W. J., Aggarwal, H., Silva, E. D., Davey, M. S., Murphy, R. F. & Agrawal, D. K., Oct 2010, In: Experimental and Molecular Pathology. 89, 2, p. 140-148 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Lymphoma 100%
  • Leukemia 98%
  • Breast Neoplasms 76%
  • human ZBTB7A protein 61%
  • Protein 49%
  47 Scopus citations

• Flt3-L increases CD4+CD25+Foxp3+ICOS + cells in the lungs of cockroach-sensitized and -challenged mice

  McGee, H. S., Edwan, J. H. & Agrawal, D. K., Mar 1 2010, In: American Journal of Respiratory Cell and Molecular Biology. 42, 3, p. 331-340 10 p.

  Research output: Contribution to journal › Article › peer-review

  • flt3 ligand protein 100%
  • Cockroaches 91%
  • Tyrosine 61%
  • Lung 35%
  • Ligand 29%
  19 Scopus citations

• Fms-like tyrosine kinase 3 ligand decreases T helper type 17 cells and suppressors of cytokine signaling proteins in the lung of house dust mite-sensitized and -challenged mice

  McGee, H. S., Stallworth, A. L., Agrawal, T., Shao, Z., Lorence, L. & Agrawal, D. K., Nov 1 2010, In: American Journal of Respiratory Cell and Molecular Biology. 43, 5, p. 520-529 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Suppressor of Cytokine Signaling Proteins 100%
  • flt3 ligand protein 93%
  • Pyroglyphidae 80%
  • Th17 Cells 74%
  • Dust 68%
  23 Scopus citations

• Insulin-like growth factor-1 induces phosphorylation of PI3K-Akt/PKB to potentiate proliferation of smooth muscle cells in human saphenous vein

  Jia, G., Mitra, A. K., Gangahar, D. M. & Agrawal, D. K., Aug 2010, In: Experimental and Molecular Pathology. 89, 1, p. 20-26 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Growth Factor 100%
  • Saphenous Vein 94%
  • Mammary Arteries 90%
  • Somatomedins 90%
  • Phosphatidylinositol 3-Kinases 83%
  28 Scopus citations

• Programmed death-1 antibody blocks therapeutic effects of T-regulatory cells in cockroach antigen-induced allergic asthma

  McGee, H. S., Yagita, H., Shao, Z. & Agrawal, D. K., Oct 1 2010, In: American Journal of Respiratory Cell and Molecular Biology. 43, 4, p. 432-442 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cockroaches 100%
  • Regulatory T-Lymphocytes 72%
  • Therapeutic Uses 60%
  • Asthma 56%
  • Block Like Crystal 49%
  37 Scopus citations
• 2011

  Calcium-activated potassium channel KCa3.1 in lung dendritic cell migration

  Shao, Z., Makinde, T. O. & Agrawal, D. K., Nov 1 2011, In: American Journal of Respiratory Cell and Molecular Biology. 45, 5, p. 962-968 7 p.

  Research output: Contribution to journal › Article › peer-review

  • TRAM-34 100%
  • Calcium-Activated Potassium Channels 62%
  • Dendritic Cells 42%
  • Cell Movement 39%
  • Sensitization 33%
  26 Scopus citations

• Cross-talk between angiotensin II and IGF-1-induced connexin 43 expression in human saphenous vein smooth muscle cells

  Jia, G., Aggarwal, A., Yohannes, A., Gangahar, D. M. & Agrawal, D. K., Aug 2011, In: Journal of Cellular and Molecular Medicine. 15, 8, p. 1695-1702 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Connexin 43 100%
  • Saphenous Vein 91%
  • Somatomedins 87%
  • Angiotensin II 79%
  • Smooth Muscle Myocytes 72%
  24 Scopus citations

• Epidermal growth factor increases LRF/Pokemon expression in human prostate cancer cells

  Aggarwal, H., Aggarwal, A. & Agrawal, D. K., Oct 2011, In: Experimental and Molecular Pathology. 91, 2, p. 496-501 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Epidermal Growth Factor 100%
  • Lymphoma 84%
  • Prostatic Neoplasms 80%
  • Tumorigenic 51%
  • Prostate 42%
  17 Scopus citations

• Expression of leukemia/lymphoma related factor (LRF/Pokemon) in human benign prostate hyperplasia and prostate cancer

  Aggarwal, H., Aggarwal, A., Hunter, W. J., Yohannes, P., Khan, A. U. & Agrawal, D. K., Apr 2011, In: Experimental and Molecular Pathology. 90, 2, p. 226-230 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Hyperplasia 100%
  • Prostate 94%
  • Lymphoma 94%
  • Leukemia 92%
  • Prostatic Neoplasms 89%
  18 Scopus citations

• Increased expression of angiopoietins and Tie2 in the lungs of chronic asthmatic mice

  Makinde, T. O. & Agrawal, D. K., Mar 1 2011, In: American Journal of Respiratory Cell and Molecular Biology. 44, 3, p. 384-393 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiopoietins 100%
  • Ovalbumin 64%
  • Airway Remodeling 45%
  • Lung 37%
  • Haematoxylin 34%
  29 Scopus citations

• Neuropeptide Y receptors in carotid plaques of symptomatic and asymptomatic patients: Effect of inflammatory cytokines

  Pankajakshan, D., Jia, G., Pipinos, I., Tyndall, S. H. & Agrawal, D. K., Jun 2011, In: Experimental and Molecular Pathology. 90, 3, p. 280-286 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuropeptide Y Receptors 100%
  • Neuropeptide Y 99%
  • Cytokines 41%
  • Smooth Muscle Myocytes 27%
  • Vascular Smooth Muscle 25%
  7 Scopus citations

• Tumor necrosis factor-α regulates p27kip expression and apoptosis in smooth muscle cells of human carotid plaques via forkhead transcription factor O1

  Jia, G., Aggarwal, A., Tyndall, S. H. & Agrawal, D. K., Feb 2011, In: Experimental and Molecular Pathology. 90, 1, p. 1-8 8 p.

  Research output: Contribution to journal › Article › peer-review

  • LY294002 100%
  • Forkhead Transcription Factors 72%
  • Silencing RNA 70%
  • Growth Factor 64%
  • Smooth Muscle Myocytes 48%
  17 Scopus citations
• 2012

  Calcitriol decreases expression of importin α3 and attenuates RelA translocation in human bronchial smooth muscle cells

  Agrawal, T., Gupta, G. K. & Agrawal, D. K., Oct 2012, In: Journal of Clinical Immunology. 32, 5, p. 1093-1103 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Karyopherins 100%
  • Calcitriol 81%
  • Smooth Muscle Myocytes 61%
  • Cell Nucleus Active Transport 18%
  • Interleukin-1 15%
  29 Scopus citations

• Chaperoning of mutant p53 protein by wild-type p53 protein causes hypoxic tumor regression

  Gogna, R., Madan, E., Kuppusamy, P. & Pati, U., Jan 20 2012, In: Journal of Biological Chemistry. 287, 4, p. 2907-2914 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oncogenic 100%
  • Mutant Proteins 76%
  • Protein 29%
  • Dimension 26%
  • Proteins 26%
  20 Scopus citations

• Gallium compound GaQ ₃-induced Ca ²⁺ signalling triggers p53-dependent and -independent apoptosis in cancer cells

  Gogna, R., Madan, E., Keppler, B. & Pati, U., May 2012, In: British Journal of Pharmacology. 166, 2, p. 617-636 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Gallium 100%
  • Reactive Oxygen Species 57%
  • Apoptosis 43%
  • Neoplasms 23%
  • Clinical Trials, Phase I 12%
  35 Scopus citations

• Oxygen cycling in conjunction with stem cell transplantation induces NOS3 expression leading to attenuation of fibrosis and improved cardiac function

  Khan, M., Meduru, S., Gogna, R., Madan, E., Citro, L., Kuppusamy, M. L., Sayyid, M., Mostafa, M., Hamlin, R. L. & Kuppusamy, P., Jan 1 2012, In: Cardiovascular Research. 93, 1, p. 89-99 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Stem Cell Transplantation 100%
  • Mesenchymal Stem Cells 77%
  • Fibrosis 70%
  • Myocardial Infarction 69%
  • Oxygen 68%
  20 Scopus citations

• p53 Ser ¹⁵ phosphorylation disrupts the p53-RPA70 complex and induces RPA70-mediated DNA repair in hypoxia

  Madan, E., Gogna, R. & Pati, U., May 1 2012, In: Biochemical Journal. 443, 3, p. 811-820 10 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Repair 100%
  • Nucleotide 88%
  • Hypoxia 85%
  • Phosphorylation 74%
  • Inhibition of Apoptosis 66%
  24 Scopus citations

• Reactive oxygen species-mediated p53 core-domain modifications determine apoptotic or necrotic death in cancer cells

  Gogna, R., Madan, E., Kuppusamy, P. & Pati, U., Mar 1 2012, In: Antioxidants and Redox Signaling. 16, 5, p. 400-412 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Apoptotic 100%
  • Reactive Oxygen Species 69%
  • Modification 48%
  • Acetylesterase 44%
  • Dioxygen 42%
  5 Scopus citations

• Re-oxygenation causes hypoxic tumor regression through restoration of p53 wild-type conformation and post-translational modifications

  Gogna, R., Madan, E., Kuppusamy, P. & Pati, U., Mar 2012, In: Cell Death and Disease. 3, 3, p. e286

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Post Translational Protein Processing 100%
  • Oxygen 69%
  • Hyperbaric Oxygenation 49%
  • Apoptosis 35%
  • Neoplasms 31%
  25 Scopus citations

• Role of matrix Gla protein in angiotensin II-induced exacerbation of vascular calcification

  Jia, G., Stormont, R. M., Gangahar, D. M. & Agrawal, D. K., Sep 1 2012, In: American Journal of Physiology - Heart and Circulatory Physiology. 303, 5

  Research output: Contribution to journal › Article › peer-review

  • matrix Gla protein 100%
  • Vascular Calcification 82%
  • Angiotensin II 61%
  • Vascular Smooth Muscle 53%
  • Smooth Muscle Myocytes 47%
  41 Scopus citations

• TIGAR induces p53-mediated cell-cycle arrest by regulation of RB-E2F1 complex

  Madan, E., Gogna, R., Kuppusamy, P., Bhatt, M., Pati, U. & Mahdi, A. A., Jul 24 2012, In: British Journal of Cancer. 107, 3, p. 516-526 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retinoblastoma 100%
  • Cell Cycle Checkpoints 82%
  • Glycolysis 33%
  • Neoplasms 27%
  • Cell Cycle 25%
  40 Scopus citations